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Person with cancer—histopathological grade, code N

Identifying and definitional attributes

Metadata item type:Help on this termData Element
Short name:Help on this termHistopathological grade
METeOR identifier:Help on this term422555
Registration status:Help on this termHealth, Standard 07/12/2011
Definition:Help on this termThe histopathological grade or differentiation in a person with cancer, as represented by a code.
Data Element Concept:Person with cancer—histopathological grade

Value domain attributes

Representational attributes

Representation class:Help on this termCode
Data type:Help on this termNumber
Format:Help on this termN
Maximum character length:Help on this term1
Permissible values:Help on this term
1Grade 1: Low grade; well differentiated, differentiated, NOS
2Grade 2: Intermediate grade, moderately differentiated, moderately well differentiated, intermediate differentiation
3Grade 3: High grade, poorly differentiated
4Grade 4: Undifferentiated, anaplastic
Supplementary values:Help on this term
9Grade or differentiation not determined, not stated or not applicable

Data element attributes

Collection and usage attributes

Guide for use:Help on this term

Histopathological grade or differentiation describes how little the tumour resembles the normal tissue from which it arose.

Only malignant tumours are graded and only one code can be recorded.

When more than one grade is documented for the primary tumour within the same specimen report, use the highest grade. For example, if grade 2-3 is documented, record the grade as 3.

If the grades differ on multiple pathology reports for the same tumour, use the value from the larger specimen (for example, the grade from a surgical excision specimen would be used over the grade from a specimen from a diagnostic biopsy).

Breast cancer coding rules:

Use the Nottingham grade (Elston-Ellis modification of Bloom-Richardson grading system). This classification only uses grades 1-3, 9.

For an invasive tumour with an in situ component, record the grade for the invasive component only. If the grade of the invasive component is not reported, record the grade as unknown.

Collection methods:Help on this term

Cancer registry use:

Collection of this data item should only be from notification and pathology reports relating to initial diagnosis and not for recurrent or metastatic disease.

Only malignant tumours are graded.

Source and reference attributes

Origin:Help on this term

World Health Organization

Commission on Cancer American College of Surgeons
Reference documents:Help on this term

Fritz A et al. 2000. International Classification of Diseases for Oncology, Third edition (ICD-O), 3rd edition. Geneva: World Health Organization

American College of Surgeons 1998. Standards of the Commission on Cancer Registry Operations and Data Standards (ROADS), Volume II, Commission on Cancer

Johnson CH & Adamo M (Editors) 2007. SEER Program Coding and Staging Manual 2007. MD 2007. Bethesda: National Cancer Institute, NIH Publication number 07-5581

Relational attributes

Related metadata references:Help on this term

Supersedes Person with cancer—histopathological grade, code N Health, Superseded 07/12/2011

Implementation in Data Set Specifications:Help on this term

Breast cancer (cancer registries) NBPDS Health, Standard 01/09/2012

DSS specific attributes +

Cancer (clinical) DSS Health, Superseded 08/05/2014

Cancer (clinical) DSS Health, Superseded 14/05/2015

Cancer (clinical) NBPDS Health, Standard 14/05/2015

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