Identifying and definitional attributes
|Metadata item type:||Value Domain|
|Registration status:||Health, Standard 14/05/2015|
|Definition:||A system of grading prostate cancer based on the sum of the primary and secondary tumour grades/patterns in sections of biopsied or resected tissue.|
|Maximum character length:||2|
Collection and usage attributes
|Guide for use:|
The Gleason score (sum) is formed by adding the primary and secondary Gleason grades/patterns together as outlined in Table 1 for radical prostatectomy specimens and Table 2 for needle core biopsy specimens. If only one grade is found in the tissue sample, then that grade (the primary Gleason grade) is multiplied by two to give the score.
Gleason grades range from 2 to 10 for radical prostatectomy specimens and 5-10 for needle core biopsy specimens (Grades 2-4 are not applicable to needle core biopsy specimens).
Table 1: Gleason scoring in radical prostatectomy specimens
Table 2: Gleason scoring in needle core biopsy specimens
* The tertiary grade is recorded separately under the item Person with cancer—histopathological grade, tertiary Gleason grade, code N
Note: Dominant (primary) grade is that which occupies the greatest area.
More extensive guidelines are available in the Prostate cancer (radical prostatectomy) structured reporting protocol (2nd Ed.) at the Royal College of Pathologists of Australasia website.
Source and reference attributes
|Submitting organisation:||Cancer Australia|
American College of Surgeons 2011. Facility Oncology Registry Data Standards: Revised for 2011. American College of Surgeons: Chicago.
Humphrey PA 2004. Gleason grading and prognostic factors in carcinoma of the prostate. Modern pathology, 17(3):p292-306.
Royal College of Pathologists of Australasia 2014. Prostate cancer (radical prostatectomy) structured reporting protocol (2nd Ed.). Royal College of Pathologists of Australasia: Sydney.
|Data elements implementing this value domain:|
Person with cancer—histopathological grade, Gleason score code N[N] Health, Standard 14/05/2015