Australian Government: Australian Institute of Health and Welfare METeOR Home Page

Person with cancer—histopathological grade, secondary Gleason grade code N

Identifying and definitional attributes

Metadata item type:Help on this termData Element
Short name:Help on this termSecondary Gleason Grade
METeOR identifier:Help on this term436185
Registration status:Help on this termHealth, Standard 14/05/2015
Definition:Help on this term

The secondary Gleason grade assigned to a prostate cancer, as represented by a code.

Context:Help on this termOnly relevant for people with prostate cancer.
Data Element Concept:Person with cancer—histopathological grade

Value domain attributes

Representational attributes

Representation class:Help on this termCode
Data type:Help on this termNumber
Format:Help on this termN
Permissible values:Help on this term
ValueMeaning
1Grade 1
2Grade 2
3Grade 3
4Grade 4
5Grade 5

Collection and usage attributes

Guide for use:Help on this term

CODE 1   Grade 1

Closely packed small regular glands forming a circumscribed rounded nodule. Not to be used for grading of needle core biopsy specimens.

CODE 2   Grade 2

Glands more loosely arranged; not quite as uniform; fairly circumscribed but may have minimal infiltration at margins. Rarely, if ever, to be used for grading of needle core biopsy specimens.

CODE 3   Grade 3

Discrete glandular units/acini with marked variation in size and shape; infiltrates in and amongst benign prostatic tissue.

CODE 4   Grade 4

Fused micro acinar glands; ill-defined glands with poorly formed lumina; large cribriform irregular glands; hypernephroid.

CODE 5   Grade 5

Minimal if any glandular differentiation – solid sheets, cords or single cells.

Collection methods:Help on this termTo be collected from pathology reports.

Source and reference attributes

Submitting organisation:Help on this termCancer Australia
Reference documents:Help on this term

Humphrey PA 2004. Gleason grading and prognostic factors in carcinoma of the prostate. Modern pathology, 17(3): 292-306

Epstein JI, Allsbrook WCJ, Amin MB and Egevad LL 2005. The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. American Journal of Surgical Pathology 29(9):1228–1242

Data element attributes

Collection and usage attributes

Guide for use:Help on this term

The secondary Gleason grade (a specific form of histopathological grade) is the tumour pattern which occupies the second greatest area of tumour based on either sections from a needle core biopsy or radical prostatectomy specimen. This is assigned by a pathologist.

Secondary Gleason grades range from 1 to 5 and are an indicator of how likely it is that a tumour will spread. A low Gleason grade means the cancer tissue is similar to normal prostate tissue and the tumour is less likely to spread; a high Gleason grade means the cancer tissue is very different from normal prostate tissue and the tumour is more likely to spread. The secondary Gleason grade is used in conjunction with the primary Gleason grade to form the Gleason score (or sum).

Collection methods:Help on this termTo be sought from pathology reports or patient medical records.
Comments:Help on this termA Gleason grade is a prognostic indicator of prostate cancer which may be used to guide treatment and assess whether appropriate treatment protocols have been used.

Source and reference attributes

Submitting organisation:Help on this termCancer Australia
Reference documents:Help on this term

American College of Surgeons 2011. Facility Oncology Registry Data Standards: Revised for 2011. American College of Surgeons: Chicago.

Humphrey PA 2004. Gleason grading and prognostic factors in carcinoma of the prostate. Modern pathology, 17(3), p292-306.

Royal College of Pathologists of Australasia 2010. Prostate cancer (radical prostatectomy) structured reporting protocol (1st Ed.). Royal College of Pathologists of Australasia: Sydney.

Relational attributes

Related metadata references:Help on this term

Is used in the formation of Person with cancer—histopathological grade, Gleason score code N[N] Health, Standard 14/05/2015

See also Person with cancer—histopathological grade, primary Gleason grade code N Health, Standard 14/05/2015

Implementation in Data Set Specifications:Help on this term

Prostate cancer (clinical) NBPDS Health, Standard 14/05/2015

My items Help on this term
Download Help on this term