Colinet defined comorbidities code N[N]

Identifying and definitional attributes

Metadata item type:Value Domain
METeOR identifier:432983
Registration status:Health, Standard 08/05/2014
Definition:A code set representing diseases or conditions present at lung cancer diagnosis that are related to non-small cell lung cancer as defined by Colinet and colleagues.

Representational attributes

Representation class:Code
Data type:Number
Maximum character length:2
Permissible values:
4Renal insufficiency
7Tobacco consumption
Supplementary values:
97Not applicable-no comorbidities present
98Unknown whether comorbidities are present
99Comorbidities are present but type not stated/inadequately described

Collection and usage attributes

Guide for use:

Record each comorbid condition, as defined by the Colinet criteria, present in the patient at the time of diagnosis for lung cancer.

The criteria were developed specifically for non-small cell lung cancer where comorbidities may be an important variable in treatment decisions and prognosis, however, record each comorbid condition for all lung cancers.

Colinet criteria for comorbidities

CODE 1   Cardiovascular

Defined as the presence of one or more of the following:

  • congestive heart failure,
  • ischaemic cardiopathy with/without myocardial infarction,
  • severe valvular cardiopathy,
  • arrhythmia requiring chronic treatment,
  • history of cerebrovascular disease,
  • hypertension, and/or
  • peripheral vascular disease

CODE 2   Respiratory

Defined as the presence of one or more of the following:

  • history of tuberculosis,
  • history of pleural effusion or pneumonia,
  • asthma,
  • pulmonary embolism,
  • chronic pulmonary insufficiency (as defined by a chronic hypoxemia less than 60 mmHg, and/or
  • chronic obstructive pulmonary disease (COPD) inducing a FEV1 less than 1.5l)

CODE 3   Neoplastic

Defined as a previous personal history of cancer excluding basal cell carcinoma of the skin and in situ carcinoma of the cervix.

CODE 4   Renal insufficiency

Defined as a creatinine clearance lower than 60 ml/min­.

CODE 5   Diabetes mellitus

Defined as diabetes treated with either oral hypoglycaemics or insulin.

CODE 6   Alcoholism

Defined as a daily consumption of:

  • more than 80g of alcohol (8 standard drinks) for men
  • more than 40g of alcohol (4 standard drinks) for women

CODE 7   Tobacco consumption

Defined as a lifelong consumption of an equivalent of at least 100 cigarettes.


The Colinet system provides criteria to define comorbidities and a scoring system whereby each comorbidity is weighted and assigned a score, then scores are added to provide the Simplified Comorbidity Score (SCS). For instance, Colinet et al. 2005 found that an SCS greater than 9 was found to be an independent prognostic factor of poor outcome in NSCLC (non-small-cell lung cancer).

For the purpose of this data item, record each comorbidity as defined by the Colinet criteria but do not score them.

Source and reference attributes

Submitting organisation:Cancer Australia
Reference documents:Colinet, B; Jacot, W et al 2005. A new simplified comorbidity score as a prognostic factor in non-small-cell lung cancer patients: description and comparison with the Charlson’s index. British Journal of Cancer 93:1098-1105

Relational attributes

Data elements implementing this value domain:

Person with cancer—comorbidities, Colinet defined comorbidities code N[N] Health, Standard 08/05/2014