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Lung cancer molecular pathology test results code N[N]

Identifying and definitional attributes

Metadata item type:Help on this termValue Domain
METeOR identifier:Help on this term432920
Registration status:Help on this termHealth, Standard 08/05/2014
Definition:Help on this termA code set representing the genetic or molecular abnormalities detected in lung cancer molecular pathology testing.

Representational attributes

Representation class:Help on this termCode
Data type:Help on this termNumber
Format:Help on this termN[N]
Maximum character length:Help on this term2
Permissible values:Help on this term
ValueMeaning
1APC - adenomatous polyposis coli
2ATM - ataxia telangiectasia mutated
3EGFR - epidermal growth factor receptor
4ERBB4 - v-erb-a erythroblastic leukaemia viral oncogene homolog 4
5ERCC1 - excision repair cross-complementing rodent repair deficiency, complementation group 1
6KDR - kinase insert domain receptor
7KRAS - v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
8NF1 - neurofibromin 1
9PTEN - phosphatase and tensin homolog
10RB1 - retinoblastoma 1
11RRM1 - ribonucleotide reductase M1
12STK11 - serine/threonine kinase 11
13TYMS - thymidylate synthetase
14P53 - tumour protein p53
15ERBB2 - v-erb-a erythroblastic leukaemia viral oncogene homolog 2
16EML4-ALK - echinoderm microtubule-associated protein-like 4 – anaplastic lymphoma kinase
17B-RAF - v-Raf murine sarcoma viral oncogene homolog B1
18ROS - C-Ros Oncogene 1, Receptor Tyrosine Kinase
19MET - Met Proto-Oncogene (Hepatocyte Growth Factor Receptor)
88Other
Supplementary values:Help on this term
97Not applicable-no abnormalities detected
98Unknown whether abnormalities detected
99Abnormalities detected but type not stated/inadequately described

Collection and usage attributes

Guide for use:Help on this term

Each code represents a HUGO Gene Nomenclature Committee (HGNC) assigned unique gene symbol. The full name, location and additional information about each gene can be obtained from their online database at www.genenames.org.

Record the code for each genetic or molecular abnormality detected.

Molecular pathology testing is usually performed for non-small cell lung cancer (NSCLC) and when the result may influence treatment.

Source and reference attributes

Submitting organisation:Help on this termCancer Australia
Reference documents:Help on this term

Harris TJR & McCormick F 2010. The molecular pathology of cancer. Nat. Rev. Clin. Oncol. 7:251-265

Royal College of Pathologists of Australasia 2010. Lung cancer structured reporting protocol. 1st Edition (Version 1.0). Surry Hills, NSW: Royal College of Pathologists of Australasia

HGNC Database, HUGO Gene Nomenclature Committee (HGNC), EMBL Outstation - Hinxton, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SD, UK. Viewed 21 June 2011, http://www.genenames.org

Relational attributes

Data elements implementing this value domain:Help on this term

Person with cancer—lung cancer molecular pathology test results, code N[N] Health, Standard 08/05/2014

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