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Gleason grade code N

Identifying and definitional attributes

Metadata item type:Help on this termValue Domain
METeOR identifier:Help on this term392730
Registration status:Help on this termHealth, Standard 14/05/2015
Definition:Help on this termAn international system of grading prostate cancer based on the tumour patterns in sections of biopsied or resected tissue.

Representational attributes

Representation class:Help on this termCode
Data type:Help on this termNumber
Format:Help on this termN
Permissible values:Help on this term
ValueMeaning
1Grade 1
2Grade 2
3Grade 3
4Grade 4
5Grade 5

Collection and usage attributes

Guide for use:Help on this term

CODE 1   Grade 1

Closely packed small regular glands forming a circumscribed rounded nodule. Not to be used for grading of needle core biopsy specimens.

CODE 2   Grade 2

Glands more loosely arranged; not quite as uniform; fairly circumscribed but may have minimal infiltration at margins. Rarely, if ever, to be used for grading of needle core biopsy specimens.

CODE 3   Grade 3

Discrete glandular units/acini with marked variation in size and shape; infiltrates in and amongst benign prostatic tissue.

CODE 4   Grade 4

Fused micro acinar glands; ill-defined glands with poorly formed lumina; large cribriform irregular glands; hypernephroid.

CODE 5   Grade 5

Minimal if any glandular differentiation – solid sheets, cords or single cells.

Collection methods:Help on this termTo be collected from pathology reports.

Source and reference attributes

Submitting organisation:Help on this termCancer Australia
Reference documents:Help on this term

Humphrey PA 2004. Gleason grading and prognostic factors in carcinoma of the prostate. Modern pathology, 17(3): 292-306

Epstein JI, Allsbrook WCJ, Amin MB and Egevad LL 2005. The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. American Journal of Surgical Pathology 29(9):1228–1242

Relational attributes

Data elements implementing this value domain:Help on this term

Person with cancer—histopathological grade, primary Gleason grade code N Health, Standard 14/05/2015

Person with cancer—histopathological grade, secondary Gleason grade code N Health, Standard 14/05/2015

Person with cancer—histopathological grade, tertiary Gleason Grade code N Health, Standard 14/05/2015

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